ZyVet's Furosemide Tablets. (Image courtesy of ZyVet Animal Health)

ZyVet Animal Health has launched an FDA-approved generic form of furosemide tablets, used for managing congestive heart failure and chronic fluid retention in cats and dogs. The medication is the most commonly used veterinary diuretic for decreasing edema and pulmonary congestion caused by cardiac, renal, or systemic conditions.

In a news release announcing the drug’s launch, ZyVet said its formulation gives veterinarians a cost-effective option for long-term therapy “without compromising dosing flexibility or product availability.”

“We are happy to participate in the animal health segment and launch the first approved generic of Furosemide in the US,” Punit Patel, president and CEO of Zydus Americas, the parent company of ZyVet, said in a company news release.

 “Managing chronic conditions in pets is a long journey, and consistency in care makes all the difference. At ZyVet, we believe in ensuring that veterinarians and pet owners have reliable, affordable options they can count on, and this launch is another step toward making quality drugs accessible to all.”

According to ZyVet, the medication is available in more than one strength for patient-specific dosing.

Congestive heart failure occurs when the heart cannot pump blood effectively, leading to fluid buildup that may leak from blood vessels. In cats and dogs, left-sided heart failure can cause fluid pulmonary edema, while right-sided heart failure leads to pleural effusion or ascites.

Common signs of heart failure in felines are difficulty breathing; a large, round abdomen due to fluid buildup in the abdomen; exercise intolerance; lethargy; hiding; weight loss; and poor appetite. In felines, coughing is not a common symptom of the disease.

Arterial thromboembolism, the formation of blood clots that travel through the bloodstream, can occur in cats with advanced heart disease. These clots most often lodge where the aorta divides into the femoral arteries, which supply the hind limbs. This blockage, called a saddle thrombus, is very painful and can cause sudden loss of function in one or both back legs, leading to paralysis in the limbs and the limb feeling cold.

 Although less common, blood clots may also lodge in the front limbs, causing the same symptoms as a saddle thrombus but on the affected front limb.

Unlike in cats, the most common sign of congestive heart failure in dogs is a persistent cough alongside difficulty breathing. Coughing may occur when resting or sleeping. Excessive panting, getting tired more easily, loss of appetite, a swollen belly, and pale or bluish gums are also signs. Dogs will heart failure may also experience generalized weight loss and muscle wasting.

ZyVet launches affordable Furosemide tablets to support long-term heart care trusted diuretic for dogs and cats now available in a generic form. News release. ZyVet Animal Health. September 15, 2025.

Barnes C. Congestive heart failure in cats. VCA Animal Hospitals. Accessed September 19, 2025. https://vcahospitals.com/know-your-pet/congestive-heart-failure-in-cats

Congestive Heart Failure in Dogs. VCA Animal Hospitals. Accessed September 19, 2025. https://vcahospitals.com/know-your-pet/congestive-heart-failure-in-dogs

Articles

Generic furosemide is used to help manage heart failure.

Generic furosemide tablets for cats and dogs is launched

Happy Friday dvm360 readers! It is officially one week since we kicked off our Fetch Coastal event in its new location, National Harbor. Thank you to all our amazing faculty as well as our attendees and exhibitors for making our first Fetch National Harbor such a success. Now that we have officially wrapped up National Harbor, our final show, Fetch Long Beach is next! You can learn more about Fetch Long Beach, including wet labs, keynotes, and register 

Before checking out the conference page, here is what you can find from this week’s news coverage on dvm360.com:

 earlier this week that the state and federal officials confirmed that highly pathogenic avian influenza was detected in a dairy cattle herd in Nebraska, making this the first known case of bird flu in Nebraska.

In this Q&A with Zachary Wright, DVM, DACVIM (Oncology) from Fetch National Harbor, he 

 more about some of the latest cancer screen tests, plus what he hoped attendees would take away from his lecture during the conference.

 of The Blast Podcast presented by dvm360, sponsored by Blue Buffalo, our host Adam Christman, DVM, MBA, welcomed Alex Miller, VMD, MS, and Phil Richmond, DVM, CAPP, CPHSA, CCFP, talked about wellbeing in veterinary medicine, plus the Florida Veterinary Medical Association's Inspire program.

The American Veterinary Medical Foundation 

 the scholarship opportunities that are available to veterinary students, including ones for veterans, those with special interests within the industry, first generation students, and more.

A team of investigators in the United Kingdom 

 oronasal mucosal melanoma for the benefit of both canines and humans. The research was made possible through support from donations to the Humanimal Trust’s Cancer Discovery Fund.

Wrap up: First case of bird flu in dairy cattle confirmed by USDA, and other news 

Note that many of the upcoming industry events are being held in person or via a combination of live and virtual learning. Please visit individual event websites for details.

https://www.veterinarydentalforum.org/future-conferences

Association of Avian Veterinarians Annual Conference & Expo

American College of Veterinary Ophthalmologists

https://www.acvoconference.org/future-conferences

American College of Veterinary Surgeons Surgery Summit

American College of Veterinary Pathologists Annual Meeting

https://acvp.org/annual-meeting/annual-meeting/

https://registration.dvm360.com/fetch-long-beach-2025

American Association of Equine Practitioners Annual Convention

Upcoming industry events and association meetings are listed.

Veterinary conference calendar (September 2025)

ZyVet Animal Health announced earlier this week that its FDA-approved generic phenylpropanolamine hydrochloride tablets have been released after receiving its approval in June 2024. This product is the first time the agency has approved a generic form of the medication. The tablets are a treatment for managing urinary incontinence in canine patients due to urethral sphincter hypotonus.

According to the release, this condition is often seen in spayed females and aging dogs and can lead to accidents that could be embarrassing or frustrating to clients. The product, now available through ZyVet, will offer a relief solution for the pet while also supporting long-term client adherence.

“Urinary incontinence affects quality of life for both pets and their families. Our phenylpropanolamine hydrochloride tablets deliver both clinical reliability and affordability, enabling veterinarians to confidently treat more patients and maintain client [adherence],” Punit Patel, president and CEO of Zydus Americas, said.

"We’re proud to offer an option that removes cost as a barrier to compassionate care. With each launch, we reinforce that innovation doesn’t need to come with a premium price tag—and that every pet should have access to high-quality treatment options,” Patel continued.

The product is available in multiple strengths to support precise dosing, and it is designed considering the needs of clients and veterinary teams.

Canine incontinence affects 20% of all spayed female dogs and up to 30% of large breed dogs, but any dog can be affected by it.

's Fetch Nashville 2025 conference, Mark J. Acierno, DVM, MBA, DACVIM (SAIM), explained more on how veterinary teams can 

, including signs, causes, and the role patient history plays for incontinence.

Collecting a patient’s history is a crucial step for diagnosing incontinence in a canine patient. When talking to clients, include questions about timing, because a puppy dribbling constantly is a significantly different scenario than a middle-aged female dog who is spayed and wetting the bed at night.

 When and where can also be important questions to ask clients. Are they urinating on the bed or next to it? If it's happening in the middle of the night, what does that look like? By considering the timing of events surrounding the urination, it can help veterinary teams tell the difference between incontinence and other conditions.

Physical examination can also determine incontinence. Veterinary teams who are examining a patient who might have incontinence should obtain a detailed examination of the patient's genitalia. They should be on the lookout for anatomic abnormalities as well as wet or stained fur or scalding and dermatitis. During his lecture, Acierno also recommended that teams have the client prevent their dog from urinating prior to the appointment.

 The patient can then urinate during the appointment to allow the team to observe the pet and gain valuable information, such as whether the pet is straining normally and whether the patient postures correctly after urinating.

ZyVet launches first generic treatment for canine urinary incontinence. News release. ZyVet Animal Health. September 15, 2025. Accessed September 18, 2025.

Generic drug for urinary incontinence in dogs receives FDA approval. 

. June 11, 2024. Accessed September 18, 2025. https://www.dvm360.com/view/generic-drug-for-urinary-incontinence-in-dogs-receives-fda-approval

Weir M, Hunter T, Ward E. Urinary incontinence (urethral incontinence) in dogs. VCA Animal Hospitals. Accessed June 5, 2025. 

https://vcahospitals.com/know-your-pet/urethral-incontinence-in-dogs

Acierno MJ. How do we turn off this spigot? managing canine incontinence. Presented at: Fetch dvm360 Conference; May 30-31, 2025; Nashville, TN.

Bautista-Alejandre A. Diagnosing canine incontinence. 

. June 5, 2025. Accessed September 18, 2025. 

https://www.dvm360.com/view/diagnosing-canine-incontinence

The approved product is used for managing urinary incontinence in canine patients.

Generic phenylpropanolamine hydrochloride tablets hit the market

Veterinary pharmaceuticals manufacturer Pegasus Laboratories, a subsidiary of PBI-Gordon Companies, celebrated the grand opening of its expanded facility in Pensacola, Florida, with a ribbon-cutting ceremony on September 18, 2025. This expansion is a critical step in Pegasus Laboratories’ continued growth and commitment to improving animal health across the nation, according to the company.

The new facility, spanning 172,000 sq ft, consists of 3 building phases that will increase manufacturing capacity, provide state-of-the-art laboratory spaces, and enhance the company’s ability to produce high-quality veterinary products for pets. The expansion was assisted by the FloridaWest Economic Development Alliance in securing a $2.5 million grant from Triumph Gulf Coast to the Pensacola-Escambia Promotion and Development Commission for the acquisition of the facility. FloridaWest served as the local economic development partner, helping to advance the project. Triumph Gulf Coast’s investment is part of its broader initiative to stimulate economic growth in the region through support for projects that create high-paying jobs and foster innovation.

“The funding of this renovated facility is an example of how targeted public investment can drive meaningful economic impact,” David Bear, president of the FloridaWest board of directors, said in a news release. “We are thrilled to see Pegasus Laboratories continue to grow in Pensacola, creating valuable, high-skilled jobs in the life sciences sector.”

Pegasus Laboratories is advancing its expansion with the creation of nearly 70 new jobs, including highly skilled positions across manufacturing, quality control, research and development, and management. Thus far, the company has invested more than $7 million in capital expenditures toward the project, with additional build-out phases anticipated to require up to $45 million to bring the full development to completion.

“By expanding our operations in Pensacola, we’re not just increasing our production capacity, but we’re also investing in the future of our employees and the communities we serve,” Steve Clifford, CEO of Pegasus Laboratories, said in a news release. “Our growth here is a direct result of the support from the FloridaWest Economic Development Alliance, Triumph Gulf Coast, and local economic development partners who understand the importance of sustainable, high-tech jobs.”

Pegasus Laboratories products are used by veterinarians across the country to treat a range of chronic conditions in pets. The new facility will enhance the company’s ability to meet growing demands for its high-quality products while adhering to the highest standards of manufacturing and animal health safety, according to the company.

Novel cardiology therapy for cats is launched

Pegasus Laboratories unveils new Pensacola facility, bringing jobs, innovation and growth to community. News release. September 18, 2025.

Pegasus Laboratories celebrated the grand opening of a larger facility in Pensacola, Florida, with a ribbon-cutting ceremony.

Pharmaceutical manufacturer expands facility to increase production

Every September, veterinary professionals and families across the country pause to reflect on the deep and enduring connections we share with our animal companions on National Pet Memorial Day. This day was established to honor the lives of pets who have passed, provides an opportunity not only for grieving families to find comfort but also for the veterinary community to reaffirm the importance of compassionate end-of-life care.

This day holds a special meaning to us at Caring Pathways, an organization dedicated exclusively to veterinary comfort care and in-home end-of-life care, because we witness daily the profound grief families experience when saying goodbye to a beloved pet. We also see how remembrance—whether through ceremony, storytelling, or simple reflection—can bring healing.

One way to help client grieve and feel support is like the memorial events Caring Pathways hosted in each of our markets—Colorado, North Carolina, and Virginia. These gatherings invited clients, both past and recent, to honor their pets in community with others who share a similar journey of loss. Families were encouraged to bring photographs, share stories, and participate in symbolic acts such as lighting candles, writing notes of remembrance on rocks, and a bubble release.

For many attendees, the events validated that their grief was seen and supported. Clients expressed gratitude for having a safe space to talk about their pets’ lives and the love that endures after loss. For our veterinary teams, the events also provided a moment to reconnect with families that we have served—reminding us why we dedicate our work to this tender part of the human–animal bond.

Research continues to affirm what veterinary professionals already know: the grief experienced after pet loss mirrors that of losing a human family member. Without opportunities for healthy grieving, clients may feel isolated or misunderstood in their sorrow. By offering memorial services, veterinary teams acknowledge that the bond between people and their pets is profound, deserving of recognition.

Creating intentional spaces for remembrance also supports resilience among veterinary professionals. Sharing stories and witnessing the ongoing impact of our care can buffer against compassion fatigue and help reframe the work as meaningful and sustaining rather than depleting.

Our commitment to honoring pets and their families does not end with the final veterinary visit. In addition to offering grief support via our Grief Support Specialist and virtual grief support groups, Caring Pathways plans to continue hosting National Pet Memorial Day events annually, ensuring that all clients—past and present—have a place to remember their cherished companions.

We encourage other practices to explore ways of engaging with clients on this day, whether through in-person gatherings, virtual tributes, or simple gestures such as posting a remembrance wall in the clinic. These efforts not only support grieving families but also strengthen the relationship between veterinary teams and the communities they serve.

National Pet Memorial Day is a reminder that end-of-life care extends beyond the moment of goodbye. As veterinary professionals, we have the privilege of walking alongside families during one of their most vulnerable times. By recognizing the importance of grief, remembrance, and continued connection, we honor both the pets who have passed and the human families who loved them.

National Pet Memorial Day fosters healing through remembrance, connecting grieving families and veterinary professionals in honoring beloved pets.